Case Study - Antituburculars

Topics: Pharmacology, Hepatitis, Tuberculosis Pages: 1 (419 words) Published: July 28, 2013
Wanda McKay is 36 years old and homeless, although she sleeps in a shelter nightly and has been going to a day program for the past 5 weeks, where she showers, receives her mail, gets some counseling, and has her meals. She is being treated daily for tuberculosis with directly observed therapy (DOT) and has been receiving this treatment for the last 6 months. She had a tubal ligation 5 years ago with no complications and is not currently sexually active. She was last tested for HIV and hepatitis C 2 months ago and was negative. She has been vaccinated for hepatitis B. She drinks, but does not use drugs, and has not been prescribed any psychiatric medications. When she was admitted into the day treatment program, her hospital records were sent indicating that she is sputum culture negative, so she is not a risk to others in close quarters. When her nurse comes to the day program to administer her meds today, she notices that the sclera of her eyes have a yellow tint to them. She is brought into the mobile center and examined by the nurse practitioner. Data obtained from the nursing assessment include the following: · The patient complains of abdominal pain, nausea. · The patient is tender to palpation of liver. · Lung sounds clear · Chest x-ray clear · Vital signs: temperature, 100.2°F; pulse, 88; respirations, 20; blood pressure, 130/80 The patient’s current medications include: isoniazid, 300 mg q day; rifampin, 600mg q day; and ethambutol, 800 mg q day. Case Study Questions 1. Provide the rationale for why Ms. McKay is prescribed amphotericin B. (5 pts) 2. What contraindications or precautions would eliminate the use of these drugs for Ms. McKay? (5 pts) 3. What patient variables are most important to consider for Ms. McKay when assessing her drug therapy? (10 pts) 4. What aspects of core drug knowledge (pharmacotherapeutics, pharmacokinetics, and pharmacodynamics) are especially relevant to consider because they may interact with the patient...
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