Drug Study Assignment

Topics: Calcium, Vitamin D, Osteoporosis Pages: 20 (3259 words) Published: January 12, 2015


PHAR 1000 – Basic Pharmocotherapeutics
Eileen J. Arellano
Norquest College
Practical Nurse- Section D01
PHAR 1000 Written Assignment
Heather Zirk RN, BN
September 15, 2014

CASE STUDY:
Name of Client: Maggie Sears
Age: 66 years old
Primary Diagnosis: Cellulitis to left leg
Secondary Diagnosis: Depression
Osteoporosis
Type 2 Diabetes Mellitus
Past Surgical History: Tonsillectomy- as child
Cholecystectomy- 15 years ago (51 years old)
Current Medications: “migraine pills”
St. John’s wort oil – for skin inflammation to left leg (for a week)

Past History: Smokes ½ a pack of cigarettes per day (since she was a teenager) Weight: 70 kg
Height: 150 cm

DOCTOR’S ORDER:
Medications:
Ancef 750 mg IV q12h
Elavil 50 mg po qhs
Calcium Carbonate 1000 mg po once daily
Vit D 1000 units po once daily
Actonel 35 mg/week po
Vagifem 10mcg tablet into the vagina qhs
Imitrex 75 mg po q4h prn for a maximum of 2 doses daily
Metformin 750 mg po TID with meals
Buffered Aspirin 650 mg po q6h prn

QUESTIONS AND ANSWERS:
1. Why are these medications ordered for Ms. Sears?
What is the therapeutic effect of each medication?

Ancef (Cefazolin)- anti infectives, first-generation cephalosporins Indication: It works by fighting bacteria in the body. Which is the cellulitis (serious bacterial skin infection) in the case of Ms. Maggie. Therapeutic Effect: Bactericidal action against susceptible bacteria. Bind to bacterial cell wall membrane, causing cell death.

Elavil (Amitriptyline) - tricyclic antidepressants
Indication: used to treat symptoms of depression.
Therapeutic Effect: anti-depressant action.
Potentiates the effect of serotonin and norepinephrine in the CNS. Has an anticholinergic properties. Calcium Carbonate (Calcium Salts)- mineral and electrolyte replacement Indication: PO- Adjunct in the prevention of postmenopausal osteoporosis Therapeutic Effect: Replacement of calcium in deficiency states. Vitamin D (Calcifediol) -vitamins

Indication: Treatment/ management of metabolic bone disease (osteoporosis) Therapeutic Effect: Promotes reabsorption of calcium and phosphorus. Treatment and
prevention of deficiency states, particularly bone manifestations.

Actonel (Risedronate)- bone reabsorption inhibitors
Indication: Prevention and treatment of postmenopausal and corticosteroid-induced osteoporosis
Therapeutic Effect: Reversal of the profression of osteoporosis with decreased fractures and other sequel.
Vagifem (Estradiol Vaginal Tablet)- hormones
Indication: Management of atrophic vaginitis that may occur with menopause. Therapeutic Effect: Restoration of hormonal deficiency states including menopause. Imitrex (Sumatriptan)- vascular headache suppressants

Indication: Acute treatment of migraine attacks.
Therapeutic Effect: Acts as selective agonist of 5-HT1 at specific vascular serotonin receptor sites, causing vasoconstriction in large intracranial arteries. Relief of acute attacks of migraine.

Metformin- antidiabetics
Indication: Management of Type 2 Diabetes Mellitus
Therapeutic Effect: Decreases hepatic glucose production. Decrease intestinal glucose absorption. Increases sensitivity to insulin.
Maintenance of blood glucose.
Buffered Aspirin (Salicylates)- non-opioid analgesics
Indication: Inflammatory disorders including Osteoarthritis. Mild-to-moderate pain
Therapeutic Effect: Produce analgesia and reduce inflammation and fever by inhibiting the production of prostaglandins. Reduction of inflammation. 2. Indicate the safe dosages for the medications ordered.

Are the dosages and route for this client safe?
Ancef (Cefazolin)
Safe Dosages: IM, IV: 500mg-2g q6hr-8hr (max 12g/day)
Doctor’s Order: 750mg q12hr, 1500mg for 24hrs
Is this Safe?: YES
Elavil (Amitriptyline)
Safe Dosages: 50-100mg at bedtime
Doctor’s Order: 50 mg q Hs
Is this Safe?: YES
Calcium Carbonate (Calcium Salts)
Safe...

References: Deglin, J.H., & Vallerand, A.H. (2005). Davi’s Drug Guide for Nurses 9th Edition. Philadelphia, PA: F.A. Davis Company.
Liley L.L., Harrington, S., & Snyder J.S. (2011). PHARMACOLOGY for Canadian Health Care Practice 2nd Canadian Edition. Ontario, Ca: MOSBY Elsvier.
Drug Guide. (n.d.) Retrieved from http://www.drugs.com/
Drug Guide Updates Davis. (n.d.) Retrieved from http://www.drugguide.com/ddo/
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